No. Your previous post that I've deleted was in german.
invalid request block size: 21573 (max 4096)
According to this stack overflow question the issue is either wrong protocol being configured in uWSGI or uWSGI is using wrong protocol when talking to Apache.
Starting uWSGI 2.0.21 (64bit) on [Mon May 22 17:28:57 2023]
compiled with version: 10.2.1 20210110 on 22 May 2023 17:25:50
os: Linux-5.10.0-21-amd64 #1 SMP Debian 5.10.162-1 (2023-01-21)
nodename: 4cfe4a4d57fb
machine: x86_64
clock source: unix
pcre jit disabled
detected number of CPU cores: 6
current working directory: /misago
detected binary path: /usr/local/bin/uwsgi
uWSGI running as root, you can use --uid/--gid/--chroot options WARNING: you are running uWSGI as root !!! (use the --uid flag)
chdir() to /misago/
your memory page size is 4096 bytes
detected max file descriptor number: 1048576
lock engine: pthread robust mutexes
thunder lock: disabled (you can enable it with --thunder-lock)
uwsgi socket 0 bound to TCP address 0.0.0.0:3031 fd 6
uWSGI running as root, you can use --uid/--gid/--chroot options WARNING: you are running uWSGI as root !!! (use the --uid flag)
Python version: 3.11.3 (main, May 4 2023, 05:53:32) [GCC 10.2.1 20210110] Python threads support is disabled. You can enable it with --enable-threads
Python main interpreter initialized at 0x7f7277357558
uWSGI running as root, you can use --uid/--gid/--chroot options WARNING: you are running uWSGI as root !!! (use the --uid flag)
your server socket listen backlog is limited to 100 connections
your mercy for graceful operations on workers is 60 seconds
mapped 671795 bytes (656 KB) for 4 cores Operational MODE: preforking
WSGI app 0 (mountpoint='') ready in 1 seconds on interpreter 0x7f7277357558 pid: 1 (default app)
uWSGI running as root, you can use --uid/--gid/--chroot options WARNING: you are running uWSGI as root !!! (use the --uid flag) uWSGI is running in multiple interpreter mode
spawned uWSGI master process (pid: 1)
spawned uWSGI worker 1 (pid: 7, cores: 1)
spawned uWSGI worker 2 (pid: 8, cores: 1)
spawned uWSGI worker 3 (pid: 9, cores: 1)
spawned uWSGI worker 4 (pid: 10, cores: 1)